Banked, engineered healthy-donor HSPCs.
Hemavive engineers healthy-donor hematopoietic stem and progenitor cells so they can be banked, cryopreserved and infused without HLA matching or donor-search delay — then tunes the same toolbox to what each disease needs.
Immune invisibility, and how long the graft should last.
These two axes — not the disease — determine how a product is engineered. Setting them independently is what lets one platform serve an emergency bridge and a lifelong correction.
Permanent
The cells stay invisible to recipient immunity for as long as they persist.
Developmental
Invisibility during engraftment, with HLA class I restored as the cells mature.
Temporary graft
A safety switch clears the cells once the host's own marrow recovers.
Durable graft
The graft is intended to persist and keep producing corrected cells from one infusion.
One toolbox, three banked products.
Radiation injury
A stockpiled, off-the-shelf hematopoietic bridge for radiation-induced marrow failure — cleared by a safety switch once host hematopoiesis recovers.
SCD & β-thalassemia
A banked one-time infusion for durable correction — partial donor chimerism can produce a disproportionate share of healthy red cells.
SCID & selected IEIs
One banked product across several SCID genotypes, with HLA class I restored as the cells mature.